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Increasing the Antigenicity of Synthetic Tumor-Associated Carbohydrate Antigens by Targeting Toll-Like Receptors

Epithelial cancer cells often over express mucins that are aberrantly glycosylated. Although it has been realized that these compounds offer exciting opportunities for the development of immunotherapy for cancer, their use is hampered by the low antigenicity of classical immunogens composed of a gly...

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Detalhes bibliográficos
Main Authors: Ingale, Sampat, Wolfert, Margreet A., Buskas, Therese, Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806797/
https://ncbi.nlm.nih.gov/pubmed/19145607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800596
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