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Increasing the Antigenicity of Synthetic Tumor-Associated Carbohydrate Antigens by Targeting Toll-Like Receptors

Epithelial cancer cells often over express mucins that are aberrantly glycosylated. Although it has been realized that these compounds offer exciting opportunities for the development of immunotherapy for cancer, their use is hampered by the low antigenicity of classical immunogens composed of a gly...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Ingale, Sampat, Wolfert, Margreet A., Buskas, Therese, Boons, Geert-Jan
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806797/
https://ncbi.nlm.nih.gov/pubmed/19145607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800596
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