Synthesis and Immunological Evaluation of a Multicomponent Cancer Vaccine Candidate Containing a Long MUC1 Glycopeptide

A fully synthetic MUC1-based cancer vaccine was designed and chemically synthesized containing an endogenous helper T-epitope (MHC class II epitope). The vaccine elicited robust IgG titers that could neutralize cancer cells by antibody-dependent cell-mediated cytotoxicity (ADCC). It also activated c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chembiochem
Egile Nagusiak: Supekar, Nitin T., Lakshminarayanan, Vani, Capicciotti, Chantelle J., Sirohiwal, Anju, Madsen, Cathy S., Wolfert, Margreet A., Cohen, Peter A., Gendler, Sandra J., Boons, Geert-Jan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975269/
https://ncbi.nlm.nih.gov/pubmed/29120508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700424
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