Synthesis and Immunological Evaluation of a Multicomponent Cancer Vaccine Candidate Containing a Long MUC1 Glycopeptide

A fully synthetic MUC1-based cancer vaccine was designed and chemically synthesized containing an endogenous helper T-epitope (MHC class II epitope). The vaccine elicited robust IgG titers that could neutralize cancer cells by antibody-dependent cell-mediated cytotoxicity (ADCC). It also activated c...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Chembiochem
Päätekijät: Supekar, Nitin T., Lakshminarayanan, Vani, Capicciotti, Chantelle J., Sirohiwal, Anju, Madsen, Cathy S., Wolfert, Margreet A., Cohen, Peter A., Gendler, Sandra J., Boons, Geert-Jan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975269/
https://ncbi.nlm.nih.gov/pubmed/29120508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700424
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