MUC1 Vaccines, Comprised of Glycosylated or Non-Glycosylated Peptides or Tumor-Derived MUC1, Can Circumvent Immunoediting to Control Tumor Growth in MUC1 Transgenic Mice

It remains challenging to produce decisive vaccines against MUC1, a tumor-associated antigen widely expressed by pancreas, breast and other tumors. Employing clinically relevant mouse models, we ruled out such causes as irreversible T-cell tolerance, inadequate avidity, and failure of T-cells to rec...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Lakshminarayanan, Vani, Supekar, Nitin T., Wei, Jie, McCurry, Dustin B., Dueck, Amylou C., Kosiorek, Heidi E., Trivedi, Priyanka P., Bradley, Judy M., Madsen, Cathy S., Pathangey, Latha B., Hoelzinger, Dominique B., Wolfert, Margreet A., Boons, Geert-Jan, Cohen, Peter A., Gendler, Sandra J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720451/
https://ncbi.nlm.nih.gov/pubmed/26788922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145920
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares