Φορτώνει......
Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABA(A)) Receptor by Binding to a Site in the Transmembrane Domain at the γ(+)-β(−) Interface
In the process of developing safer general anesthetics, isomers of anesthetic ethers and barbiturates have been discovered that act as convulsants and inhibitors of γ-aminobutyric acid type A receptors (GABA(A)Rs) rather than potentiators. It is unknown whether these convulsants act as negative allo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Biol Chem |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645599/ https://ncbi.nlm.nih.gov/pubmed/26229099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.672006 |
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