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A New View of Ras Isoforms in Cancers

Does small GTPase K-Ras4A have a single state or two states, one resembling K-Ras4B and the other N-Ras? A recent study of K-Ras4A made the remarkable observation that even in the absence of the palmitoyl K-Ras4A can be active at the plasma membrane. Importantly, this suggests that K-Ras4A may exist...

詳細記述

保存先:
書誌詳細
出版年:Cancer Res
主要な著者: Nussinov, Ruth, Tsai, Chung-Jung, Chakrabarti, Mayukh, Jang, Hyunbum
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644351/
https://ncbi.nlm.nih.gov/pubmed/26659836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1536
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