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A New View of Pathway-Driven Drug Resistance in Tumor Proliferation

Defeating drug resistance in proliferation is challenging. Here we propose unifying signaling in cell proliferation with two core pathways, each embodying multiple alternative pathways. We consider drug resistance through an alternative proliferation pathway – within the same or within the other cor...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Nussinov, Ruth, Tsai, Chung-Jung, Jang, Hyunbum
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403593/
https://ncbi.nlm.nih.gov/pubmed/28245913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2017.02.001
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