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A New View of Pathway-Driven Drug Resistance in Tumor Proliferation

Defeating drug resistance in proliferation is challenging. Here we propose unifying signaling in cell proliferation with two core pathways, each embodying multiple alternative pathways. We consider drug resistance through an alternative proliferation pathway – within the same or within the other cor...

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Vydáno v:Trends Pharmacol Sci
Hlavní autoři: Nussinov, Ruth, Tsai, Chung-Jung, Jang, Hyunbum
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403593/
https://ncbi.nlm.nih.gov/pubmed/28245913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2017.02.001
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