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Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers
Are the dimer structures of active Ras isoforms similar? This question is significant since Ras can activate its effectors as a monomer; however, as a dimer, it promotes Raf’s activation and MAPK (mitogen-activated protein kinase) cell signalling. In the present study, we model possible catalytic do...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7830773/ https://ncbi.nlm.nih.gov/pubmed/27057007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160031 |
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