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Searching target sites on DNA by proteins: Role of DNA dynamics under confinement

DNA-binding proteins (DBPs) rapidly search and specifically bind to their target sites on genomic DNA in order to trigger many cellular regulatory processes. It has been suggested that the facilitation of search dynamics is achieved by combining 3D diffusion with one-dimensional sliding and hopping...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Mondal, Anupam, Bhattacherjee, Arnab
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627088/
https://ncbi.nlm.nih.gov/pubmed/26400158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv931
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