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Searching target sites on DNA by proteins: Role of DNA dynamics under confinement

DNA-binding proteins (DBPs) rapidly search and specifically bind to their target sites on genomic DNA in order to trigger many cellular regulatory processes. It has been suggested that the facilitation of search dynamics is achieved by combining 3D diffusion with one-dimensional sliding and hopping...

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Publicat a:Nucleic Acids Res
Autors principals: Mondal, Anupam, Bhattacherjee, Arnab
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627088/
https://ncbi.nlm.nih.gov/pubmed/26400158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv931
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