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Searching target sites on DNA by proteins: Role of DNA dynamics under confinement

DNA-binding proteins (DBPs) rapidly search and specifically bind to their target sites on genomic DNA in order to trigger many cellular regulatory processes. It has been suggested that the facilitation of search dynamics is achieved by combining 3D diffusion with one-dimensional sliding and hopping...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Mondal, Anupam, Bhattacherjee, Arnab
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627088/
https://ncbi.nlm.nih.gov/pubmed/26400158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv931
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