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Searching target sites on DNA by proteins: Role of DNA dynamics under confinement

DNA-binding proteins (DBPs) rapidly search and specifically bind to their target sites on genomic DNA in order to trigger many cellular regulatory processes. It has been suggested that the facilitation of search dynamics is achieved by combining 3D diffusion with one-dimensional sliding and hopping...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Mondal, Anupam, Bhattacherjee, Arnab
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627088/
https://ncbi.nlm.nih.gov/pubmed/26400158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv931
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