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Search by proteins for their DNA target site: 2. The effect of DNA conformation on the dynamics of multidomain proteins

Multidomain transcription factors, which are especially abundant in eukaryotic genomes, are advantageous to accelerate the search kinetics for target site because they can follow the intersegment transfer via the monkey-bar mechanism in which the protein forms a bridged intermediate between two dist...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Bhattacherjee, Arnab, Levy, Yaakov
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227779/
https://ncbi.nlm.nih.gov/pubmed/25324311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku933
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