Dynamic Strategies for Target-Site Search by DNA-Binding Proteins

Gene regulatory proteins find their target sites on DNA remarkably quickly; the experimental binding rate for lac repressor is orders-of-magnitude higher than predicted by free diffusion alone. It has been proposed that nonspecific binding aids the search by allowing proteins to slide and hop along...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Díaz de la Rosa, Mario A., Koslover, Elena F., Mulligan, Peter J., Spakowitz, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Nucleic Acid
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884260/
https://ncbi.nlm.nih.gov/pubmed/20550907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.055
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki