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Dynamic Strategies for Target-Site Search by DNA-Binding Proteins
Gene regulatory proteins find their target sites on DNA remarkably quickly; the experimental binding rate for lac repressor is orders-of-magnitude higher than predicted by free diffusion alone. It has been proposed that nonspecific binding aids the search by allowing proteins to slide and hop along...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Biophysical Society
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884260/ https://ncbi.nlm.nih.gov/pubmed/20550907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.055 |
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