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How proteins bind to DNA: target discrimination and dynamic sequence search by the telomeric protein TRF1

Target search as performed by DNA-binding proteins is a complex process, in which multiple factors contribute to both thermodynamic discrimination of the target sequence from overwhelmingly abundant off-target sites and kinetic acceleration of dynamic sequence interrogation. TRF1, the protein that b...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wieczór, Miłosz, Czub, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737604/
https://ncbi.nlm.nih.gov/pubmed/28633355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx534
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