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How proteins bind to DNA: target discrimination and dynamic sequence search by the telomeric protein TRF1
Target search as performed by DNA-binding proteins is a complex process, in which multiple factors contribute to both thermodynamic discrimination of the target sequence from overwhelmingly abundant off-target sites and kinetic acceleration of dynamic sequence interrogation. TRF1, the protein that b...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737604/ https://ncbi.nlm.nih.gov/pubmed/28633355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx534 |
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