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Searching target sites on DNA by proteins: Role of DNA dynamics under confinement

DNA-binding proteins (DBPs) rapidly search and specifically bind to their target sites on genomic DNA in order to trigger many cellular regulatory processes. It has been suggested that the facilitation of search dynamics is achieved by combining 3D diffusion with one-dimensional sliding and hopping...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Mondal, Anupam, Bhattacherjee, Arnab
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627088/
https://ncbi.nlm.nih.gov/pubmed/26400158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv931
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