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How Proteins Search for Their Specific Sites on DNA: The Role of DNA Conformation

It is known since the early days of molecular biology that proteins locate their specific targets on DNA up to two orders-of-magnitude faster than the Smoluchowski three-dimensional diffusion rate. An accepted explanation of this fact is that proteins are nonspecifically adsorbed on DNA, and sliding...

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Bibliografski detalji
Glavni autori: Hu, Tao, Grosberg, A. Yu., Shklovskii, B. I.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414577/
https://ncbi.nlm.nih.gov/pubmed/16461402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078162
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