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How Proteins Search for Their Specific Sites on DNA: The Role of DNA Conformation
It is known since the early days of molecular biology that proteins locate their specific targets on DNA up to two orders-of-magnitude faster than the Smoluchowski three-dimensional diffusion rate. An accepted explanation of this fact is that proteins are nonspecifically adsorbed on DNA, and sliding...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Biophysical Society
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1414577/ https://ncbi.nlm.nih.gov/pubmed/16461402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078162 |
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