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High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice
Although improvements in technology for the isolation of potential therapeutic antibodies have made the process increasingly predictable, the development of biologically active monoclonal antibodies (mAbs) into drugs can often be impeded by developability issues such as poor expression, solubility,...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | MAbs |
|---|---|
| Prif Awduron: | , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Taylor & Francis
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622737/ https://ncbi.nlm.nih.gov/pubmed/26047159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1043503 |
| Tagiau: |
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