Biophysical properties of the clinical-stage antibody landscape

Antibodies are a highly successful class of biological drugs, with over 50 such molecules approved for therapeutic use and hundreds more currently in clinical development. Improvements in technology for the discovery and optimization of high-potency antibodies have greatly increased the chances for...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Jain, Tushar, Sun, Tingwan, Durand, Stéphanie, Hall, Amy, Houston, Nga Rewa, Nett, Juergen H., Sharkey, Beth, Bobrowicz, Beata, Caffry, Isabelle, Yu, Yao, Cao, Yuan, Lynaugh, Heather, Brown, Michael, Baruah, Hemanta, Gray, Laura T., Krauland, Eric M., Xu, Yingda, Vásquez, Maximiliano, Wittrup, K. Dane
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293111/
https://ncbi.nlm.nih.gov/pubmed/28096333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616408114
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