Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors

Here we describe an industry-wide collaboration aimed at assessing the binding properties of a comprehensive panel of monoclonal antibodies (mAbs) against programmed cell death protein 1 (PD-1), an important checkpoint protein in cancer immunotherapy and validated therapeutic target, with well over...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Brown, Michael E., Bedinger, Daniel, Lilov, Asparouh, Rathanaswami, Palaniswami, Vásquez, Maximiliano, Durand, Stéphanie, Wallace-Moyer, Ian, Zhong, Lihui, Nett, Juergen H., Burnina, Irina, Caffry, Isabelle, Lynaugh, Heather, Sinclair, Melanie, Sun, Tingwan, Bukowski, John, Xu, Yingda, Abdiche, Yasmina Noubia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058304/
https://ncbi.nlm.nih.gov/pubmed/32134960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229206
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