Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms

Por Bedinger, Daniel, Lao, Llewelyn, Khan, Shireen, Lee, Steve, Takeuchi, Toshihiko, Mirza, Amer M.
Publicado no MAbs (2015)

Selective Allosteric Antibodies to the Insulin Receptor for the Treatment of Hyperglycemic and Hypoglycemic Disorders

Por Issafras, Hassan, Bedinger, Daniel H., Corbin, John A., Goldfine, Ira D., Bhaskar, Vinay, White, Mark L., Rubin, Paul, Scannon, Patrick J.
Publicado no J Diabetes Sci Technol (2014)

Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets

Por Ching, Kathryn H., Collarini, Ellen J., Abdiche, Yasmina N., Bedinger, Daniel, Pedersen, Darlene, Izquierdo, Shelley, Harriman, Rian, Zhu, Lei, Etches, Robert J., van de Lavoir, Marie-Cecile, Harriman, William D., Leighton, Philip A.
Publicado no MAbs (2017)

A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library

Por Adler, Adam S., Bedinger, Daniel, Adams, Matthew S., Asensio, Michael A., Edgar, Robert C., Leong, Renee, Leong, Jackson, Mizrahi, Rena A., Spindler, Matthew J., Bandi, Srinivasa Rao, Huang, Haichun, Tawde, Pallavi, Brams, Peter, Johnson, David S.
Publicado no MAbs (2018)

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

Por Lackey, Denise E., Lynch, Christopher J., Olson, Kristine C., Mostaedi, Rouzbeh, Ali, Mohamed, Smith, William H., Karpe, Fredrik, Humphreys, Sandy, Bedinger, Daniel H., Dunn, Tamara N., Thomas, Anthony P., Oort, Pieter J., Kieffer, Dorothy A., Amin, Rajesh, Bettaieb, Ahmed, Haj, Fawaz G., Permana, Paska, Anthony, Tracy G., Adams, Sean H.
Publicado em 2013

Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity

Por Roell, Marina K., Issafras, Hassan, Bauer, Robert J., Michelson, Kristen S., Mendoza, Nerissa, Vanegas, Sandra I., Gross, Lisa M., Larsen, Paul D., Bedinger, Daniel H., Bohmann, David J., Nonet, Genevieve H., Liu, Naichi, Lee, Steve R., Handa, Masahisa, Kantak, Seema S., Horwitz, Arnold H., Hunter, John J., Owyang, Alexander M., Mirza, Amer M., Corbin, John A., White, Mark L.
Publicado em 2010

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control

Por Bhaskar, Vinay, Goldfine, Ira D., Bedinger, Daniel H., Lau, Angela, Kuan, Hua F., Gross, Lisa M., Handa, Masahisa, Maddux, Betty A., Watson, Susan R., Zhu, Shirley, Narasimha, Ajay J., Levy, Raphael, Webster, Lynn, Wijesuriya, Sujeewa D., Liu, Naichi, Wu, Xiaorong, Chemla-Vogel, David, Tran, Catarina, Lee, Steve R., Wong, Steve, Wilcock, Diane, White, Mark L., Corbin, John A.
Publicado em 2012

Improved Glucose Metabolism In Vitro and In Vivo by an Allosteric Monoclonal Antibody That Increases Insulin Receptor Binding Affinity

Por Corbin, John A., Bhaskar, Vinay, Goldfine, Ira D., Bedinger, Daniel H., Lau, Angela, Michelson, Kristen, Gross, Lisa M., Maddux, Betty A., Kuan, Hua F., Tran, Catarina, Lao, Llewelyn, Handa, Masahisa, Watson, Susan R., Narasimha, Ajay J., Zhu, Shirley, Levy, Raphael, Webster, Lynn, Wijesuriya, Sujeewa D., Liu, Naichi, Wu, Xiaorong, Chemla-Vogel, David, Lee, Steve R., Wong, Steve, Wilcock, Diane, White, Mark L.
Publicado em 2014

Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: A potential new approach for the treatment of hyperinsulinemic hypoglycemia

Por Corbin, John A, Bhaskar, Vinay, Goldfine, Ira D, Issafras, Hassan, Bedinger, Daniel H, Lau, Angela, Michelson, Kristen, Gross, Lisa M, Maddux, Betty A, Kuan, Hua F, Tran, Catarina, Lao, Llewelyn, Handa, Masahisa, Watson, Susan R, Narasimha, Ajay J, Zhu, Shirley, Levy, Raphael, Webster, Lynn, Wijesuriya, Sujeewa D, Liu, Naichi, Wu, Xiaorong, Chemla-Vogel, David, Lee, Steve R, Wong, Steve, Wilcock, Diane, Rubin, Paul, White, Mark L
Publicado em 2014