Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

Elevated blood branched-chain amino acids (BCAA) are often associated with insulin resistance and type 2 diabetes, which might result from a reduced cellular utilization and/or incomplete BCAA oxidation. White adipose tissue (WAT) has become appreciated as a potential player in whole body BCAA metab...

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Hauptverfasser: Lackey, Denise E., Lynch, Christopher J., Olson, Kristine C., Mostaedi, Rouzbeh, Ali, Mohamed, Smith, William H., Karpe, Fredrik, Humphreys, Sandy, Bedinger, Daniel H., Dunn, Tamara N., Thomas, Anthony P., Oort, Pieter J., Kieffer, Dorothy A., Amin, Rajesh, Bettaieb, Ahmed, Haj, Fawaz G., Permana, Paska, Anthony, Tracy G., Adams, Sean H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680678/
https://ncbi.nlm.nih.gov/pubmed/23512805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00630.2012
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