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Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms

Transforming growth factor (TGF)β levels are elevated in, and drive the progression of, numerous disease states such as advanced metastatic cancer and systemic and ocular fibrosis. There are 3 main isoforms, TGFβ1, 2, and 3. As multiple TGFβ isoforms are involved in disease processes, maximal therap...

詳細記述

保存先:
書誌詳細
出版年:MAbs
主要な著者: Bedinger, Daniel, Lao, Llewelyn, Khan, Shireen, Lee, Steve, Takeuchi, Toshihiko, Mirza, Amer M.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966579/
https://ncbi.nlm.nih.gov/pubmed/26563652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1115166
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