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Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin

Botulism, a disease of humans characterized by prolonged paralysis, is caused by botulinum neurotoxins (BoNTs), the most poisonous substances known. There are seven serotypes of BoNT (A–G) which differ from each other by 34–64% at the amino acid level. Each serotype is uniquely recognized by polyclo...

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Detalhes bibliográficos
Main Authors: Garcia-Rodriguez, C., Geren, I.N., Lou, J., Conrad, F., Forsyth, C., Wen, W., Chakraborti, S., Zao, H., Manzanarez, G., Smith, T.J., Brown, J., Tepp, W.H., Liu, N., Wijesuriya, S., Tomic, M.T., Johnson, E.A., Smith, L.A., Marks, J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038462/
https://ncbi.nlm.nih.gov/pubmed/21149386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq111
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