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Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display

Botulinum neurotoxin (BoNT), the most poisonous substance known, causes naturally occurring human disease (botulism) and is one of the top six biothreat agents. Botulism is treated with polyclonal antibodies produced in horses which are associated with a high incidence of systemic reactions. Human m...

Полное описание

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Библиографические подробности
Главные авторы: Levy, R., Forsyth, C.M., LaPorte, S.L, Geren, I.N., Smith, L.A., Marks, J.D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994578/
https://ncbi.nlm.nih.gov/pubmed/17059824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.084
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