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Sequence Variation within Botulinum Neurotoxin Serotypes Impacts Antibody Binding and Neutralization
The botulinum neurotoxins (BoNTs) are category A biothreat agents which have been the focus of intensive efforts to develop vaccines and antibody-based prophylaxis and treatment. Such approaches must take into account the extensive BoNT sequence variability; the seven BoNT serotypes differ by up to...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1231122/ https://ncbi.nlm.nih.gov/pubmed/16113261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5450-5457.2005 |
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