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Epitope Mapping of Neutralizing Botulinum Neurotoxin A Antibodies by Phage Display
Single-chain antibodies neutralize activity and bind nonoverlapping epitopes of botulinum A neurotoxin. Two phage display epitope libraries were constructed from the 1.3 kb of binding domain cDNA. The minimal epitopes selected against the single-chain Fv-Fc antibodies correspond to conformational ep...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC98787/ https://ncbi.nlm.nih.gov/pubmed/11553596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6511-6514.2001 |
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