Epitope Mapping of Neutralizing Botulinum Neurotoxin A Antibodies by Phage Display

Single-chain antibodies neutralize activity and bind nonoverlapping epitopes of botulinum A neurotoxin. Two phage display epitope libraries were constructed from the 1.3 kb of binding domain cDNA. The minimal epitopes selected against the single-chain Fv-Fc antibodies correspond to conformational ep...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Mullaney, B. P., Pallavicini, M. G., Marks, J. D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.10.6511-6514.2001
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