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Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody

The botulinum neurotoxins (BoNTs) cause the paralytic human disease botulism and are one of the highest-risk threat agents for bioterrorism. To generate a pharmaceutical to prevent or treat botulism, monoclonal antibodies (mAbs) were generated by phage display and evaluated for neutralization of BoN...

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Main Authors: Nowakowski, A., Wang, C., Powers, D. B., Amersdorfer, P., Smith, T. J., Montgomery, V. A., Sheridan, R., Blake, R., Smith, L. A., Marks, J. D.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC123259/
https://ncbi.nlm.nih.gov/pubmed/12177434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172229899
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