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Characterization of Neutralizing Antibodies and Identification of Neutralizing Epitope Mimics on the Clostridium botulinum Neurotoxin Type A

Clostridium botulinum neurotoxin type A (BTx-A) is known to inhibit the release of acetylcholine at the neuromuscular junctions and synapses and to cause neuroparalysis and death. In this study, we have identified two monoclonal antibodies, BT57-1 and BT150-3, which protect ICR mice against lethal d...

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Udgivet i:Appl Environ Microbiol
Principais autores: Wu, Han-Chung, Yeh, Chia-Tsui, Huang, Yue-Ling, Tarn, Lih-Jeng, Lung, Chien-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
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Methods
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93001/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11425742/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.67.7.3201-3207.2001
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