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High-Affinity, Protective Antibodies to the Binding Domain of Botulinum Neurotoxin Type A
Monoclonal antibodies (MAbs) were prepared against the putative binding domain of botulinum neurotoxin A (BoNT/A), a nontoxic 50-kDa fragment. Initially, all fusion products were screened against the holotoxin BoNT/A and against the binding fragment, BoNT/A H(C). Eleven neutralizing hybridomas were...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC97921/ https://ncbi.nlm.nih.gov/pubmed/11119555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.570-574.2001 |
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