High-Affinity, Protective Antibodies to the Binding Domain of Botulinum Neurotoxin Type A

Monoclonal antibodies (MAbs) were prepared against the putative binding domain of botulinum neurotoxin A (BoNT/A), a nontoxic 50-kDa fragment. Initially, all fusion products were screened against the holotoxin BoNT/A and against the binding fragment, BoNT/A H(C). Eleven neutralizing hybridomas were...

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Detalles Bibliográficos
Main Authors: Pless, Dorothy D., Torres, Edna R., Reinke, Emily K., Bavari, Sina
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC97921/
https://ncbi.nlm.nih.gov/pubmed/11119555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.570-574.2001
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