Characterization of Neutralizing Antibodies and Identification of Neutralizing Epitope Mimics on the Clostridium botulinum Neurotoxin Type A

Clostridium botulinum neurotoxin type A (BTx-A) is known to inhibit the release of acetylcholine at the neuromuscular junctions and synapses and to cause neuroparalysis and death. In this study, we have identified two monoclonal antibodies, BT57-1 and BT150-3, which protect ICR mice against lethal d...

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Библиографические подробности

Опубликовано в::	Appl Environ Microbiol
Главные авторы:	Wu, Han-Chung, Yeh, Chia-Tsui, Huang, Yue-Ling, Tarn, Lih-Jeng, Lung, Chien-Cheng
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2001
Предметы:	Methods
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11425742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.67.7.3201-3207.2001
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