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An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies

The effectiveness of therapeutic monoclonal antibodies (mAbs) is governed not only by their bioactivity, but also by their biophysical properties. Assays for rapidly evaluating the biophysical properties of mAbs are valuable for identifying those most likely to exhibit superior properties such as hi...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Estep, Patricia, Caffry, Isabelle, Yu, Yao, Sun, Tingwan, Cao, Yuan, Lynaugh, Heather, Jain, Tushar, Vásquez, Maximiliano, Tessier, Peter M, Xu, Yingda
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622688/
https://ncbi.nlm.nih.gov/pubmed/25790175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1016694
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