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An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies

The effectiveness of therapeutic monoclonal antibodies (mAbs) is governed not only by their bioactivity, but also by their biophysical properties. Assays for rapidly evaluating the biophysical properties of mAbs are valuable for identifying those most likely to exhibit superior properties such as hi...

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Detalles Bibliográficos
Publicado en:MAbs
Autores principales: Estep, Patricia, Caffry, Isabelle, Yu, Yao, Sun, Tingwan, Cao, Yuan, Lynaugh, Heather, Jain, Tushar, Vásquez, Maximiliano, Tessier, Peter M, Xu, Yingda
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622688/
https://ncbi.nlm.nih.gov/pubmed/25790175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1016694
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