Biophysical properties of the clinical-stage antibody landscape

Antibodies are a highly successful class of biological drugs, with over 50 such molecules approved for therapeutic use and hundreds more currently in clinical development. Improvements in technology for the discovery and optimization of high-potency antibodies have greatly increased the chances for...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Jain, Tushar, Sun, Tingwan, Durand, Stéphanie, Hall, Amy, Houston, Nga Rewa, Nett, Juergen H., Sharkey, Beth, Bobrowicz, Beata, Caffry, Isabelle, Yu, Yao, Cao, Yuan, Lynaugh, Heather, Brown, Michael, Baruah, Hemanta, Gray, Laura T., Krauland, Eric M., Xu, Yingda, Vásquez, Maximiliano, Wittrup, K. Dane
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293111/
https://ncbi.nlm.nih.gov/pubmed/28096333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616408114
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