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IGFBP2 potentiates nuclear EGFR-STAT3 signaling

Insulin-like growth factor binding protein 2 (IGFBP2) is a pleiotropic oncogenic protein that has both extracellular and intracellular functions. Despite a clear causal role in cancer development, the tumor-promoting mechanisms of IGFBP2 are poorly understood. The contributions of intracellular IGFB...

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Publicat a:Oncogene
Autors principals: Chua, Corrine Yingxuan, Liu, Yuexin, Granberg, Kirsi J., Hu, Limei, Haapasalo, Hannu, Annala, Matti J., Cogdell, David E., Verploegen, Maartje, Moore, Lynette M., Fuller, Gregory N., Nykter, Matti, Cavenee, Webster K., Zhang, Wei
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615268/
https://ncbi.nlm.nih.gov/pubmed/25893308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.131
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