Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas

BACKGROUND: Inhibitors of fibroblast growth factor receptors (FGFRs) have recently arisen as a promising treatment option for patients with FGFR alterations. Gene fusions involving FGFR3 and transforming acidic coiled-coil protein 3 (TACC3) have been detected in diffuse gliomas and other malignancie...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Granberg, Kirsi J, Annala, Matti, Lehtinen, Birgitta, Kesseli, Juha, Haapasalo, Joonas, Ruusuvuori, Pekka, Yli-Harja, Olli, Visakorpi, Tapio, Haapasalo, Hannu, Nykter, Matti, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570261/
https://ncbi.nlm.nih.gov/pubmed/28379477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox028
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