The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

Fusion genes are chromosomal aberrations that are found in many cancers and can be used as prognostic markers and drug targets in clinical practice. Fusions can lead to production of oncogenic fusion proteins or to enhanced expression of oncogenes. Several recent studies have reported that some fusi...

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Main Authors: Parker, Brittany C., Annala, Matti J., Cogdell, David E., Granberg, Kirsi J., Sun, Yan, Ji, Ping, Li, Xia, Gumin, Joy, Zheng, Hong, Hu, Limei, Yli-Harja, Olli, Haapasalo, Hannu, Visakorpi, Tapio, Liu, Xiuping, Liu, Chang-gong, Sawaya, Raymond, Fuller, Gregory N., Chen, Kexin, Lang, Frederick F., Nykter, Matti, Zhang, Wei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2013
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561838/
https://ncbi.nlm.nih.gov/pubmed/23298836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67144
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