The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

Fusion genes are chromosomal aberrations that are found in many cancers and can be used as prognostic markers and drug targets in clinical practice. Fusions can lead to production of oncogenic fusion proteins or to enhanced expression of oncogenes. Several recent studies have reported that some fusi...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Parker, Brittany C., Annala, Matti J., Cogdell, David E., Granberg, Kirsi J., Sun, Yan, Ji, Ping, Li, Xia, Gumin, Joy, Zheng, Hong, Hu, Limei, Yli-Harja, Olli, Haapasalo, Hannu, Visakorpi, Tapio, Liu, Xiuping, Liu, Chang-gong, Sawaya, Raymond, Fuller, Gregory N., Chen, Kexin, Lang, Frederick F., Nykter, Matti, Zhang, Wei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2013
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561838/
https://ncbi.nlm.nih.gov/pubmed/23298836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67144
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