The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

Fusion genes are chromosomal aberrations that are found in many cancers and can be used as prognostic markers and drug targets in clinical practice. Fusions can lead to production of oncogenic fusion proteins or to enhanced expression of oncogenes. Several recent studies have reported that some fusi...

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Hlavní autoři: Parker, Brittany C., Annala, Matti J., Cogdell, David E., Granberg, Kirsi J., Sun, Yan, Ji, Ping, Li, Xia, Gumin, Joy, Zheng, Hong, Hu, Limei, Yli-Harja, Olli, Haapasalo, Hannu, Visakorpi, Tapio, Liu, Xiuping, Liu, Chang-gong, Sawaya, Raymond, Fuller, Gregory N., Chen, Kexin, Lang, Frederick F., Nykter, Matti, Zhang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561838/
https://ncbi.nlm.nih.gov/pubmed/23298836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67144
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