Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas

BACKGROUND: Fibroblast growth factor receptors (FGFRs) are well-known proto-oncogenes in several human malignancies and are currently therapeutically targeted in clinical trials. Among glioma subtypes, activating FGFR1 alterations have been observed in a subpopulation of pilocytic astrocytomas while...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Lehtinen, Birgitta, Raita, Annina, Kesseli, Juha, Annala, Matti, Nordfors, Kristiina, Yli-Harja, Olli, Zhang, Wei, Visakorpi, Tapio, Nykter, Matti, Haapasalo, Hannu, Granberg, Kirsi J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415775/
https://ncbi.nlm.nih.gov/pubmed/28468611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3274-9
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