Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network

Insulin-like growth factor-binding protein 2 (IGFBP2) is increasingly recognized as a glioma oncogene, emerging as a target for therapeutic intervention. In this study, we used an integrative approach to characterizing the IGFBP2 network, combining transcriptional profiling of human glioma with vali...

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Detalhes bibliográficos
Main Authors: Holmes, Kristen M., Annala, Matti, Chua, Corrine Y. X., Dunlap, Sarah M., Liu, Yuexin, Hugen, Niek, Moore, Lynette M., Cogdell, David, Hu, Limei, Nykter, Matti, Hess, Kenneth, Fuller, Gregory N., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295320/
https://ncbi.nlm.nih.gov/pubmed/22345562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120375109
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