Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies

Insulin-like growth factor binding protein 2 (IGFBP2) overexpression is common in high-grade glioma and is both a strong biomarker of aggressive behaviour and a well-documented prognostic factor. IGFBP2 is a member of the secreted IGFBP family that functions by interacting with circulating IGFs to m...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Phillips, Lynette M., Zhou, Xinhui, Cogdell, David E., Chua, Corrine Yingxuan, Huisinga, Anouk, Hess, Kenneth R., Fuller, Gregory N., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915980/
https://ncbi.nlm.nih.gov/pubmed/27125842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4734
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