IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas

The levels of insulin-like growth factor-binding protein 2 (IGFBP2) are elevated during progression of many human cancers. By using a glial-specific transgenic mouse system (RCAS/Ntv-a), we reported previously that IGFBP2 is an oncogenic factor for glioma progression in combination with platelet-der...

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Detalles Bibliográficos
Main Authors: Moore, Lynette M., Holmes, Kristen M., Smith, Sarah M., Wu, Ying, Tchougounova, Elena, Uhrbom, Lene, Sawaya, Raymond, Bruner, Janet M., Fuller, Gregory N., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757856/
https://ncbi.nlm.nih.gov/pubmed/19805356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900807106
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