IGFBP2 potentiates nuclear EGFR-STAT3 signaling

Insulin-like growth factor binding protein 2 (IGFBP2) is a pleiotropic oncogenic protein that has both extracellular and intracellular functions. Despite a clear causal role in cancer development, the tumor-promoting mechanisms of IGFBP2 are poorly understood. The contributions of intracellular IGFB...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Chua, Corrine Yingxuan, Liu, Yuexin, Granberg, Kirsi J., Hu, Limei, Haapasalo, Hannu, Annala, Matti J., Cogdell, David E., Verploegen, Maartje, Moore, Lynette M., Fuller, Gregory N., Nykter, Matti, Cavenee, Webster K., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615268/
https://ncbi.nlm.nih.gov/pubmed/25893308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.131
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