Wordt geladen...

Mutational Analysis of the Putative High-Affinity Propofol Binding Site in Human β3 Homomeric GABA(A) Receptors

Propofol is a sedative and anesthetic agent that can both activate GABA(A) receptors and potentiate receptor activation elicited by submaximal concentrations of the transmitter. A recent modeling study of the β3 homomeric GABA(A) receptor postulated a high-affinity propofol binding site in a hydroph...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Mol Pharmacol
Hoofdauteurs: Eaton, Megan M., Cao, Lily Q., Chen, Ziwei, Franks, Nicholas P., Evers, Alex S., Akk, Gustav
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576687/
https://ncbi.nlm.nih.gov/pubmed/26206487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.100347
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!