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Modulation of the human ρ1 GABA(A) receptor by inhibitory steroids

RATIONALE: Modulators of the ρ1 GABA(A) receptor may be useful in the treatment of visual, sleep, and cognitive disorders. Neuroactive steroids and analogues have been shown to modulate ρ1 receptor function but the molecular mechanisms are poorly understood. OBJECTIVES: We employed electrophysiology...

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Detalhes bibliográficos
Main Authors: Eaton, Megan M., Lim, You Bin, Covey, Douglas F., Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048647/
https://ncbi.nlm.nih.gov/pubmed/24317445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3379-z
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